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Phages Mediate Bacterial Self-Recognition

Identifiers: SRA: SRP166899
BioProject: PRJNA498536
Study Type: 
Abstract: Cells are social, and self-recognition is an important and conserved aspect of group behavior where cells assist kin and antagonize non-kin to conduct group behavior such as foraging for food and biofilm formation. However, the role of the common bacterial cohabitant, phage, in kin recognition, has not been explored. Here we find that a boundary (demarcation line) is formed between different swimming Escherichia coli strains but not between identical clones; hence, motile bacterial cells discriminate between self and non-self. The basis for this self-recognition is a novel, 49 kb, T1-type, lytic phage of the family siphoviridae (named here SW1) that controls formation of the demarcation line by utilizing one of the host's cryptic prophage proteins, YfdM, to propagate

Related SRA data

1 ( 1 samples )
1 (49.1kbp; 135.2kb)
Additional objects:
File type count
nanopore 1