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The skin microbiome of DOCK8-deficient patients

Identifiers: SRA: SRP157584
BioProject: PRJNA471898
Study Type: 
Abstract: Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive, combined immunodeficiency that features cutaneous viral-associated manifestations, including molluscum contagiosum, herpesvirus infections, and warts (HPV infections) along with atopic dermatitis. We present a comprehensive investigation of the skin microbiome of DOCK8-deficient patients, focusing on the skin virome. We utilized both reference-based and reference-free analyses to investigate the microbial (viral) 'dark matter' and discovered a large number of novel human papillomavirus genomes.
Center Project: human skin metagenome
External Link: /pubmed:30397357

Related SRA data

320 ( 320 samples )
879 (674.0Gbp; 279.6Gb)
Additional objects:
File type count
fastq 1758