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ß-D-N(4)-hydroxycytidine is a potent anti-alphavirus compound that induces high level of mutations in viral genome

Identifiers: SRA: SRP124735
BioProject: PRJNA417833
GEO: GSE106752
Study Type: 
Other
Abstract: The goal of this project was the analysis of virus variants resistant to ß-D-N(4)-hydroxycytidine. Overall design: Venezuelan equine encephalitis virus TC-83 was passaged on Vero cells for 20 passages in the presence or absence of ß-D-N(4)-hydroxycytidine. Virus samples were collected at passages 0, 5 10, 15 and 20. Total virion RNAs were isolated and sequenced.

Related SRA data

Experiments:
13 ( 13 samples )
Runs:
13 (5.1Gbp; 2.4Gb)