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RNA-seq of human fibroblasts during replicative senescence

Identifiers: SRA: SRP050179
BioProject: PRJNA268292
GEO: GSE63577
Study Type: 
Transcriptome Analysis
Abstract: Senescent human fibroblasts were compared to young proliferating fibroblasts. Five different cell lines were compared. Illumina sequencing (HiSeq2000) was applied to generate 50bp single-end reads. Jena Centre for Systems Biology of Ageing - JenAge (www.jenage.de) Overall design: 48 samples: 3 biological replicates for each group: young proliferating and senescent BJ cells; young proliferating and senescent Wi-38 cells; young proliferating and senescent IMR-90 cells; 5 population doubling from young proliferating to senescent cell for HFF and MRC-5 cells
Center Project: GSE63577
External Link: /pubmed:26339636

Related SRA data

Experiments:
45 ( 45 samples )
Runs:
45 (93.5Gbp; 61.0Gb)