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GPBAR1 agonism has a broad impact on blocking macrophage activation

Identifiers: SRA: SRP041826
BioProject: PRJNA246549
GEO: GSE57494
Study Type: 
Transcriptome Analysis
Abstract: Human D14+ / CD16+ monocytes were treated with GPBAR1 agonists or controls, and were stimulated with interferon gamma and LPS. At 6 and 24 hours, the cells were profiled by RNAseq Overall design: 40 total samples, 5 per group with eight groups. Individual donors used for multiple comparisons, so paired analysis is possible. Control samples include unstimulated cells, and stimulated cells treated with vehicle control (DMSO).
Center Project: Homo sapiens
External Link: /pubmed:24967665

Related SRA data

40 ( 40 samples )
40 (51.9Gbp; 33.7Gb)