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Changes in gene expression profiles of circulating B cells after influenza vaccination in healthy human subjects

Identifiers: SRA: SRP020491
BioProject: PRJNA196147
GEO: GSE45734
Study Type: 
Transcriptome Analysis
Abstract: Daily sampling of peripheral blood from human subjects vaccinated for influenza was done immediately before vaccination and for 10 days after vaccination. In B cells, 90% of transcriptomic variation in subjects who received influenza vaccine within the previous three years was explained by a single temporal pattern unique to the individual. A common set of 742 genes was strongly correlated with the migration of differentiating plasma cell subtypes. Overall design: Five subjects, 11 time points per subject (pre-vaccination and daily for 10 days post-vaccination)
Center Project: GSE45734
External Link: /pubmed:23900141

Related SRA data

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55 (48.6Gbp; 27.1Gb)