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Genome Sequencing in Pancreatic Ductal Adenocarcinoma

Identifiers: SRA: SRP014665
BioProject: PRJNA171808
dbGaP: phs000516
Study Type: 
Abstract: Pancreatic ductal adenocarcinomas (PDAC) is the 11th most common cancer in the USA but the 4th in fatalities. The onset and progression of cancer is driven by extensive rearrangement and mutation of the genome. We combined our capability to capture and enrich exome DNA with the next generation sequencing capacity to allow us to detect and characterize the somatic mutation profile of 24 patients with PDAC. Patient samples were collected by the Elkins Pancreatic Center in the Baylor College of Medicine Department of Surgery. Sequencing of the pancreatic ductal adenocarcinoma is one of the NHGRI Center Initiated Projects in progress in the Human Genome Sequencing Center at Baylor College of Medicine. These data are also contributed to an ICGC study and will be published with the ICGC collaborators.

The SRA runs contain human sequence

These data are available through the dbGaP authorized access system.

Related SRA data

166 ( 118 samples )
166 (1.3Tbp; 637.3Gb)