skip to main content

GSE38824: Analysis of IRF8 binding site and histone modification in IRF8-induced monocyte differentiation

Identifiers: SRA: SRP013833
GEO: GSE38824
Study Type: 
Epigenetics
Abstract: Summary: Chromatins were prepared from myeloid progenitor cell line Tot2 cells transduced with retrovirus for control MSCV or MSCV-IRF8. Chromatin immunoprecipitation (ChIP) was carried out by using anti-IRF8 antibody, anti-PU.1 antibody or anti-histone H3K4me1 antibody. ChIP-Seq peaks were identified using the FindPeaks tool in the HOMER package or SICER with input DNA tags as background distribution. Potential IRF8-direct target genes were identified based on ChIP-Seq and the alteration of expression by IRF8-induction. Overall Design: Examination of 2 transcription factor occupancy and 1 histone modifications in myeloid progenitor cells and monocyte-like cells differetiated by IRF8 expression
Center Project: GSE38824: Analysis of IRF8 binding site and histone modification in IRF8-induced monocyte differentiation
External Links: GEO Series
/gds:200038824

Related SRA data

Experiments:
6 ( 6 samples )
Runs:
6 (10.9Gbp; 6.2Gb)