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Genome-wide microRNA expression analysis of clear cell Renal Cell Carcinoma by next generation deep sequencing

Identifiers: SRA: SRP012546
BioProject: PRJNA162397
GEO: GSE37616
Study Type: 
Transcriptome Analysis
Abstract: MicroRNAs (miRNAs), non-coding RNAs regulating gene expression, are frequently aberrantly expressed in human cancers. Next-generation deep sequencing technology enables genome-wide expression profiling of known miRNAs and discovery of novel miRNAs at unprecedented quantitative and qualitative accuracy. Deep sequencing was performed on 22 fresh frozen clear cell renal cell carcinoma (ccRCC), 11 non-tumoral renal cortex (NRC) samples and 2 ccRCC cell lines (n=35). The 22 ccRCCs patients belonged to 3 prognostic sub-groups, i.e. Those without disease recurrence, with recurrence and with metastatic disease at diagnosis Overall design: Deep sequencing was performed on 22 fresh frozen clear cell renal cell carcinoma (ccRCC), 11 non-tumoral renal cortex (NRC) samples and 2 ccRCC cell lines (n=35). The 22 ccRCCs patients belonged to 3 prognostic sub-groups, i.e. Those without disease recurrence, with recurrence and with metastatic disease at diagnosis.
Center Project: GSE37616
External Link: /pubmed:22745662

Related SRA data

Experiments:
35 ( 35 samples )
Runs:
35 (2.9Gbp; 2.1Gb)