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TARGET: Kidney - Rhabdoid Tumor (RT)

Identifiers: SRA: SRP012005
BioProject: PRJNA89539
dbGaP: phs000470
Study Type: 
Abstract: To further explore some more aggressive subtypes in pediatric cancer already under study in OCG, CGCI is partnering with TARGET initiative to support extensive sequencing analysis of three hard to treat childhood cancers: refractory to treatment cases of acute myeloid leukemia and two rare kidney tumors; clear cell sarcoma of the kidney and rhabdoid tumor (RT). Rhabdoid tumors are a rare, very aggressive type of kidney tumor of infancy, and patients typically have a poor prognosis. Up to 40 patient cases of matched tumor and normal samples, as well as some established cell lines, will undergo whole genome sequencing, miRNA-seq and mRNA-seq, DNA methyl-seq and ChIP-seq to generate a comprehensive profile and hopefully facilitate the development of better therapeutic options for this tumor subtype. All cases can be sorted according to data type via the Case Matrix on the TARGET Data Matrix. Please visit the TARGET website listed above for additional information... (for more see dbGaP study page.)

The SRA runs contain human sequence

These data are available through the dbGaP authorized access system.

Related SRA data

511 ( 234 samples )
604 (35.4Tbp; 15.4Tb)