skip to main content

AML Sequencing Project

Identifiers: SRA: SRP000918
BioProject: PRJNA74783
BioProject: PRJNA74785
dbGaP: phs000159
Study Type: 
Other
Abstract: We used massively parallel sequencing technology to sequence the genomic DNA of tumor cells (leukemic bone marrow) and normal cells (skin biopsy) obtained from patients with Acute Myeloid Leukemia (AML). Patients had either de novo AML (AML with no prior diagnosis of a hematologic disease or exposure to chemotherapy), secondary AML (occurring after a prior diagnosis of myelodysplastic syndromes (MDS)), or therapy-related AML (occurring after exposure to prior chemotherapy). We identified somatic mutations in the tumor genomes, including single nucleotide variants, insertions, deletions, and structural variants.

The SRA runs contain human sequence

These data are available through the dbGaP authorized access system.

Related SRA data

Experiments:
717 ( 635 samples )
Runs:
2313 (39.8Tbp; 17.5Tb)
Additional objects:
File type count
assembled contigs 126