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RNA sequencing of pancreatic adenocarcinoma (PDAC) xenograft samples

Identifiers: SRA: ERP022034
BioProject: PRJEB19942
Projet Carte d’Identite des Tumeurs LIGUE NATIONALE CONTRE LE CANCER: E-MTAB-5039
Study Type: 
Transcriptome Analysis
Abstract: Pancreatic adenocarcinoma (PDAC) is one of the most lethal human malignancies and a major health problem. Patient-derived xenografts (PDX) are appearing as a prime approach for preclinical studies despite being insufficiently characterized as a model of the human disease and its diversity. We generated subcutaneous PDX from PDAC samples obtained either surgically or using diagnostic biopsies (endoscopic ultrasound guided fine needle aspirate). The extensive multiomics characterization of the xenografts demonstrated that PDX is a suitable model for preclinical studies, representing the diversity of the primary cancers. this dataset, describe the RNA sequencing data used in the multiomics study.
Description: Pancreatic adenocarcinoma (PDAC) is one of the most lethal human malignancies and a major health problem. Patient-derived xenografts (PDX) are appearing as a prime approach for preclinical studies despite being insufficiently characterized as a model of the human disease and its diversity. We generated subcutaneous PDX from PDAC samples obtained either surgically or using diagnostic biopsies (endoscopic ultrasound guided fine needle aspirate). The extensive multiomics characterization of the xenografts demonstrated that PDX is a suitable model for preclinical studies, representing the diversity of the primary cancers. this dataset, describe the RNA sequencing data used in the multiomics study.
External Link: E-MTAB-5039 in ArrayExpress

Related SRA data

Experiments:
30 ( 30 samples )
Runs:
58 (650.1Gbp; 217.2Gb)
Additional objects:
File type count
fastq 116