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³Cells-of-origin transcriptional memory governs self-renewal of MLL cancer stem cells²

Identifiers: SRA: ERP010755
BioProject: PRJEB9628
'ERIC SO LAB LEUKAEMIA AND STEM CELL BIOLOGY GROUP DEPARTMENT OF HAEMATOLOGICAL MEDICINE KING''S COLLEGE LONDON': E-MTAB-3647
'Eric So lab Leukaemia and Stem Cell Biology Group Department of Haematological Medicine King''s College London': E-MTAB-3647
Study Type: 
Transcriptome Analysis
Abstract: From mice, strand-specific RNA-Seq of granulocyte-myeloid progenitors (GMP) and hematopoietic stem cells (HSC). Cancer stem cells (CSC) were created with MLL-ENL transfections using puromycin for both GMP and HSCs. Further knock-outs were created of Î?-catenin (Ctnnb1) and Hoxa9.
Description: From mice, strand-specific RNA-Seq of granulocyte-myeloid progenitors (GMP) and hematopoietic stem cells (HSC). Cancer stem cells (CSC) were created with MLL-ENL transfections using puromycin for both GMP and HSCs. Further knock-outs were created of Î?-catenin (Ctnnb1) and Hoxa9.

Related SRA data

Experiments:
36 ( 36 samples )
Runs:
36 (138.4Gbp; 78.4Gb)